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Written by bioXplorer
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Sep 25, 2007 at 10:00 AM |
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Name: ProSite Description: The PROSITE database consists of a large collection of biologically meaningful signatures that are 10 described as patterns or profiles. Each signature is linked to a documentation that provides useful biological information on the protein family, domain or functional site identified by the signature. The PROSITE database is now complemented by a series 15 of rules that can give more precise information about specific residues. During the last 2 years, the documentation and the ScanProsite web pages were redesigned to add more functionalities.
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Last Updated ( Sep 30, 2007 at 03:40 AM )
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Written by bioXplorer
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Sep 25, 2007 at 09:36 AM |
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Name: InterPro Description: InterPro is an integrated resource for protein families, domains and functional sites, which integrates the following protein signature databases: PROSITE, PRINTS, ProDom, Pfam, SMART, TIGRFAMs, PIRSF, SUPERFAMILY, Gene3D and PANTHER. The latter two new member databases have been integrated since the last publication in this journal. There have been several new developments in InterPro, including an additional reading field, new database links, extensions to the web interface and additional match XML files. InterPro has always provided matches to UniProtKB proteins on the website and in the match XML file on the FTP site. Additional matches to proteins in UniParc (UniProt archive) are now available for download in the new match XML files only. The latest InterPro release (13.0) contains more than 13 000 entries, covering over 78% of all proteins in UniProtKB.
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Last Updated ( Sep 30, 2007 at 03:40 AM )
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UniProt - The Universal Protein Resource |
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Written by bioXplorer
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Sep 22, 2007 at 10:58 AM |
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Name: UniProt - The Universal Protein Resource Description: The Universal Protein Resource (UniProt) provides a central resource on protein sequences and functional annotation with three database components, each addressing a key need in protein bioinformatics. The UniProt Knowledgebase (UniProtKB), comprising the manually annotated UniProtKB/Swiss-Prot section and the automatically annotated UniProtKB/ TrEMBLsection, is the preeminent storehouse of protein annotation. The extensive cross-references, functional and feature annotations and literaturebased evidence attribution enable scientists to analyse proteinsand query acrossdatabases.TheUniProtReference Clusters (UniRef) speed similarity searches via sequence space compression by merging sequences that are 100% (UniRef100), 90% (UniRef90) or 50% (UniRef50) identical. Finally, the UniProt Archive (UniParc) stores all publicly available protein sequences, containing the history of sequence data with links to the source databases. UniProt databases continue to grow in size and in availability of information. Recent and upcoming changes to database contents, formats, controlled vocabularies and services are described. New download availability includes all major releases of UniProtKB, sequence collections by taxonomic division and complete proteomes.
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Last Updated ( Sep 25, 2007 at 09:43 AM )
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Databases 
