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RFAM - RNA families database of alignments and CMs

Written by bioXplorer

Sep 22, 2007 at 10:39 AM

Name: RFAM - RNA families database of alignments and CMs

Description: Rfam is a joint project involving researchers based at the Wellcome Trust Sanger Institute, Cambridge, UK and Janelia Farm, Ashburn, VA, USA. Rfam is a large collection of multiple sequence alignments and covariance models covering many common non-coding RNA families. For each family in Rfam you can:

    * View and download multiple sequence alignments
    * Read family annotation
    * Examine species distribution of family members
    * Follow links to otherdatabases

In conjunction with the INFERNAL software suite, Rfam can be used to annotate sequences (including complete genomes) for homologues to known non-coding RNAs. Please read important information about using Rfam for genome annotation. We provide pre-calculated lists of putative RNAs in over 200 complete genomes, and a web search facility for short sequences.

Rfam makes use of a large amount of available data, especially published multiple sequence alignments, and repackages these data in a single searchable and sustainable resource.

Home page: http://www.sanger.ac.uk/Software/Rfam/

File repository: ftp://ftp.sanger.ac.uk/pub/databases/Rfam/

Updates: Unregular

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