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UniProt - The Universal Protein Resource

Written by bioXplorer

Sep 22, 2007 at 10:58 AM

Name: UniProt - The Universal Protein Resource

Description: The Universal Protein Resource (UniProt) provides a central resource on protein sequences and functional annotation with three database components, each addressing a key need in protein bioinformatics. The UniProt Knowledgebase (UniProtKB), comprising the manually annotated UniProtKB/Swiss-Prot section and the automatically annotated UniProtKB/ TrEMBLsection, is the preeminent storehouse of protein annotation. The extensive cross-references, functional and feature annotations and literaturebased evidence attribution enable scientists to analyse proteinsand query acrossdatabases.TheUniProtReference Clusters (UniRef) speed similarity searches via sequence space compression by merging sequences that are 100% (UniRef100), 90% (UniRef90) or 50% (UniRef50) identical. Finally, the UniProt Archive (UniParc) stores all publicly available protein sequences, containing the history of sequence data with links to the source databases. UniProt databases continue to grow in size and in availability of information. Recent and upcoming changes to database contents, formats, controlled vocabularies and services are described. New download availability includes all major releases of UniProtKB, sequence collections by taxonomic division and complete proteomes.

Home page: http://www.ebi.uniprot.org/

File repository: ftp://ftp.uniprot.org/pub/databases/uniprot/current_release/knowledgebase/

Updates: Biweekly updates for Knowledgebase

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