Title: Lipoic Acid: Energy Production, Antioxidant Activity and Health Effects

Author(s): Mulchand S. Patel, Lester Packer

Series: Oxidative Stress and Disease

Publisher: CRC

ISBN: 1420045377

Publication: 2008

Pages: 556

Description: Unique in its two-fold protective function, alpha-lipoic acid has drawn unprecedented interest for its role as a coenzyme in mitochondrial energy metabolism and as an antioxidant and cell redox modulator. Divided into three sections, this book covers the latest discoveries in the chemistry, biological action, and significance of alpha-lipoic acid in energy production, antioxidant activity, and health. Section I reviews the discovery, molecular structure, biosynthesis, and characterization of lipoic acid. Section II describes metabolic aspects and human pharmacodynamics and explains its role in energy production and antioxidant activity. Section III discusses clinical aspects and the treatment of metabolic syndromes and loss of mitochondrial function with lipoic acid supplementation.

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